Plant Transcription Factor Database
Previous version: v3.0
Nicotiana tabacum
BBR-BPC Family
Species TF ID Description
XP_016435499.1BBR-BPC family protein
XP_016435500.1BBR-BPC family protein
XP_016438751.1BBR-BPC family protein
XP_016442557.1BBR-BPC family protein
XP_016451527.1BBR-BPC family protein
XP_016451528.1BBR-BPC family protein
XP_016451530.1BBR-BPC family protein
XP_016451531.1BBR-BPC family protein
XP_016451534.1BBR-BPC family protein
XP_016451535.1BBR-BPC family protein
XP_016451536.1BBR-BPC family protein
XP_016451537.1BBR-BPC family protein
XP_016451538.1BBR-BPC family protein
XP_016451539.1BBR-BPC family protein
XP_016451540.1BBR-BPC family protein
XP_016470419.1BBR-BPC family protein
XP_016473618.1BBR-BPC family protein
XP_016473619.1BBR-BPC family protein
XP_016473620.1BBR-BPC family protein
XP_016473621.1BBR-BPC family protein
XP_016473622.1BBR-BPC family protein
XP_016473624.1BBR-BPC family protein
XP_016473625.1BBR-BPC family protein
XP_016473626.1BBR-BPC family protein
XP_016473627.1BBR-BPC family protein
XP_016478822.1BBR-BPC family protein
XP_016480188.1BBR-BPC family protein
XP_016480189.1BBR-BPC family protein
XP_016480190.1BBR-BPC family protein
XP_016489002.1BBR-BPC family protein
XP_016490468.1BBR-BPC family protein
XP_016499158.1BBR-BPC family protein
XP_016499159.1BBR-BPC family protein
XP_016509512.1BBR-BPC family protein
XP_016509513.1BBR-BPC family protein
XP_016509514.1BBR-BPC family protein
XP_016509515.1BBR-BPC family protein
XP_016509516.1BBR-BPC family protein
XP_016515335.1BBR-BPC family protein
BBR/BPC Family Introduction

We identified BASIC PENTACYSTEINE1 (BPC1) as a regulator of the homeotic Arabidopsis thaliana gene SEEDSTICK (STK), which controls ovule identity, and characterized its mechanism of action. A combination of tethered particle motion analysis and electromobility shift assays revealed that BPC1 is able to induce conformational changes by cooperative binding to purine-rich elements present in the STK regulatory sequence. Analysis of STK expression in the bpc1 mutant showed that STK is upregulated. Our results give insight into the regulation of gene expression in plants and provide the basis for further studies to understand the mechanisms that control ovule identity in Arabidopsis.

Kooiker M, Airoldi CA, Losa A, Manzotti PS, Finzi L, Kater MM, Colombo L.
BASIC PENTACYSTEINE1, a GA binding protein that induces conformational changes in the regulatory region of the homeotic Arabidopsis gene SEEDSTICK.
Plant Cell. 2005 Mar;17(3):722-9. Epub 2005 Feb 18.
PMID: 15722463

BBR is nuclear targeted and is a characterized nuclear localization signal (NLS) sequence, a DNA-binding domain extended up to 90 aa at the C-terminus and a putative N-terminal activation domain. The corresponding gene has no introns and is ubiquitously expressed in barley tissues. In co-transfection experiments, BBR activates (GA/TC)8-containing promoters, and its overexpression in tobacco leads to a pronounced leaf shape modification. BBR has properties of a GAGA-binding factor, but the corresponding gene has no sequence homology to Trl and Psq of Drosophila, which encode functionally analogous proteins. In Arabidopsis, (GA/TC)8 repeats occur particularly within 1500 bp upstream of gene start codons included in some homeodomain genes of different classes. The data presented suggest that expression of the barley BKn3 is regulated, at least in part, by the binding of the transcription factor BBR to GA/TC repeats.

Santi L, Wang Y, Stile MR, Berendzen K, Wanke D, Roig C, Pozzi C, Muller K, Muller J, Rohde W, Salamini F.
The GA octodinucleotide repeat binding factor BBR participates in the transcriptional regulation of the homeobox gene Bkn3.
Plant J, 2003. 34(6): p. 813-26.
PMID: 12795702